The detection and classification of membrane-spanning proteins. DNA sequencing with chain-terminating inhibitors. Genome instability in a region of human DNA enriched in Alu repeat sequences. A unique cytogenetic-clinicopathological association. Leukemia and the disruption of normal hematopoiesis. Acute myelomonocytic leukemia with abnormal eosinophils and inv 16 or t 16;16 has a favorable prognosis.

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The t 5;14 chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.

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Use of synthetic peptides corresponding to physiological sites as probes for substrate recognition requirements. Gene bccm T-cell growth factor: Interleukin 2 mRNA induction in human lymphocytes: A cDNA library of tumour cells was screened with an interleukin 2 gene-specific probe.

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes.


Three cases of translocation 8;16 p11;p13 observed in acute myelomonocytic leukemia: The t 14;18 chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. Please review our privacy policy. Associated Data Supplementary Materials.

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A new method for predicting signal sequence cleavage sites. Studies on the phosphorylation of myelin basic protein by protein kinase C and adenosine 3′: Nucleotide sequence of a t 14;18 chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome Alu-Alu recombination deletes exons encoding transmembrane and cytoplasmic domains. Genome instability in a region of human DNA enriched in Alu repeat sequences.

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. Alu sequences transcription in X.

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A new specific chromosomal rearrangement, t 8;16 p11;p13in acute monocytic leukaemia. A simple method for bcj the hydropathic character of a protein.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Two distinct loci on the short arm of chromosome 16 are involved in myeloid leukemia.


Mutation in LDL receptor: Translocations, master genes, and differences between the origins of acute and chronic leukemias. Distinctive chromosomal abnormalities in histologic subtypes of non-Hodgkin’s lymphoma. DNA sequencing with chain-terminating inhibitors. The detection and classification of membrane-spanning proteins. Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia. Human interleukin 2 gene is located on chromosome 4. Human proto-oncogene c-mos maps to 8q Chromosome abnormalities in poorly differentiated lymphocytic lymphoma.

A unique cytogenetic-clinicopathological association. A t 4;16 q26;p Author information Copyright and License information Disclaimer. Open in a separate window. Essential role of the interleukin 2-interleukin 2 receptor pathway in thymocyte maturation in vivo.